加里·库珀
Gary Cooper
饰：Henry Louis 'Lou' Gehrig
特雷莎·怀特
Muriel Teresa Wright
饰：Eleanor Twitchell
贝比·鲁斯
Babe Ruth
饰：Babe Ruth
沃尔特·布伦南
Walter Brennan
饰：Sam Blake
丹·德亚
Dan Duryea
饰：Hank Hanneman
埃尔莎·扬森
Elsa Janssen
饰：Christina 'Mom' Gehrig
路德维希·施托塞尔
Ludwig Stössel
饰：Henry 'Pop' Gehrig (as Ludwig Stossel)
弗吉尼亚·吉尔摩
Virginia Gilmore
饰：Myra Tinsley
比尔·迪基
Bill Dickey
饰：Bill Dickey
厄尼·亚当斯
Ernie Adams
饰：Miller Huggins
皮埃尔·沃特金斯
Pierre Watkin
饰：Frank Twitchell
Harry Harvey Jr.
饰：Joe McCarthy
鲍勃·穆塞尔
Bob Meusel
饰：Bob Meusel (as Robert W. Meusel)
马克·凯尼格
Mark Koenig
饰：Mark Koenig
比尔·斯特恩
Bill Stern
饰：Bill Stern
艾迪生·理查兹
Addison Richards
饰：Jim
哈迪·奥尔布赖特
Hardie Albright
饰：Van Tuyl
爱德华·菲尔丁
Edward Fielding
饰：Clinic doctor
乔治·莱西
George Lessey
饰：Walter Otto, Mayor of New Rochelle
埃德加·巴里尔
Edgar Barrier
饰：Hospital doctor
Douglas Croft
饰：Lou Gehrig, as a boy
Gene Collins
饰：Billy
戴维·霍尔特
David Holt
饰：Billy, at 17
Veloz
饰：Specialty dancer
Yolanda
饰：Specialty dancer
Ray Noble
饰：Band (as Ray Noble and His Orchestra)
Ed Agresti
饰：Barber (uncredited)
Ernie Alexander
饰：Bellhop with flowers (uncredited)
Walter Anthony
Walter Anthony
饰：Merril (uncredited)
Hooper Atchley
饰：Lathered man in barber shop (uncredited)
Bettye Avery
Bettye Avery
饰：Nightclub singer (uncredited)
Rebecca Bohannen
饰：Little girl (uncredited)
Lynton Brent
饰：Photographer in hospital (uncredited)
Roy Brent
饰：Yankee ballplayer (uncredited)
Betty Brewer
饰：Little girl (uncredited)
Don Brodie
饰：Girl show barker (uncredited)
Charles Cane
饰：Plumber (uncredited)
Jack Carr
饰：Plumber (uncredited)
Burr Caruth
饰：Village storekeeper (uncredited)
艾德·钱德勒
Eddy Chandler
饰：Motorcycle cop #2 (uncredited)
莱恩·钱德勒
Lane Chandler
饰：Mark, Yankee player in locker room (uncredited)
Bill Chaney
Bill Chaney
饰：Newsboy (uncredited)
Jack Chapin
饰：Photographer (uncredited)
Janet Chapman
饰：Tessie (uncredited)
斯潘塞·查特斯
Spencer Charters
饰：Mr. Larsen (uncredited)
Porter Chase
饰：Weight guesser (uncredited)
戴恩·克拉克
Dane Clark
饰：Fraternity boy (uncredited)
海尼·康克林
Heinie Conklin
饰：Wallpaper hanger (uncredited)
Hal Cooke
饰：Man in cab (uncredited)
Clancy Cooper
饰：Motorcycle cop #1 (uncredited)
约翰·达海姆
John Daheim
饰：Reporter in hospital (uncredited)
Eva Dennison
饰：Mrs. Worthington (uncredited)
Lester Dorr
饰：Disappointed fan #1 (uncredited)
Lorna Dunn
饰：Clinic nurse (uncredited)
Peter Du Rey
饰：Photographer in hospital (uncredited)
吉姆·法利
Jim Farley
饰：Spectator (uncredited)
弗兰克·费伦
Frank Faylen
饰：Yankee third base coach (uncredited)
Walter Fenner
饰：Dentist (uncredited)
帕特·弗莱厄蒂
Edmund J. Flaherty
饰：Yankee ballplayer (uncredited)
Charles Flynn
饰：Fraternity boy (uncredited)
Rosina Galli
饰：Mrs. Fabrini (uncredited)
Jack Gardner
饰：Tunnel of Love barker (uncredited)
Vaughan Glaser
饰：Doctor in Gehrig home (uncredited)
玛丽·戈登
Mary Gordon
饰：Maid (uncredited)
George Guhl
饰：Second paper hanger (uncredited)
Eddie Hall
饰：Reporter in hospital room (uncredited)
维顿·海沃斯
Vinton Hayworth
饰：Fraternity boy (uncredited)
哈里·海登
Harry Hayden
饰：Department store manager (uncredited)
Oscar 'Dutch' Hendrian
饰：Furniture mover (uncredited)
John Hiestand
饰：Announcer (uncredited)
Earle Hodgins
饰：Bottle game operator (uncredited)
费伊·霍尔德内斯
Fay Holderness
饰：Spectator (uncredited)
John Ince
饰：Man in box seat (uncredited)
Mitchell Ingraham
饰：Barber (uncredited)
Jack Irwin
Jack Irwin
饰：Photographer in hospital (uncredited)
Sheldon Jett
饰：Sportsman at ballgame (uncredited)
约翰·凯洛格
John Kellogg
饰：Fraternity boy (uncredited)
唐纳德·柯尔
Donald Kerr
饰：Photographer (uncredited)
Richard Kipling
饰：Broker (uncredited)
Pat Lane
饰：Wheel of Chance barker (uncredited)
Larry Lawson
Larry Lawson
饰：Barker (uncredited)
雷克斯·利斯
Rex Lease
饰：Spectator (uncredited)
Theodore Lorch
饰：Neighbor leaning through window (uncredited)
Frank Lyman
饰：Fraternity boy (uncredited)
Dave Manley
饰：Mayor Fiorello LaGuardia (uncredited)
Francisco Marán
饰：Rathskeller headwaiter (uncredited)
Ralph McCullough
饰：Reporter in hospital (uncredited)
George McDonald
George McDonald
饰：Wally Pipp, Yankee first baseman (uncredited)
Matt McHugh
饰：Strength machine operator (uncredited)
James McNamara
饰：Rathskeller manager (uncredited)
John Merkyl
饰：Spectator (uncredited)
Howard M. Mitchell
饰：Sportsman at ballgame (uncredited)
Irving Mitchell
饰：Headwaiter (uncredited)
Pat Moriarity
饰：Policeman in 1915 (uncredited)
汤姆·尼尔
Tom Neal
饰：Fraternity boy (uncredited)
Patsy O'Byrne
饰：Scrubwoman (uncredited)
George Offerman
饰：Freshman (uncredited)
John B. Old
John B. Old
饰：Reporter (uncredited)
Garry Owen
饰：Scorecard vendor (uncredited)
Sarah Padden
Sarah Padden
饰：Mrs. Roberts, Gehrig neighbor (uncredited)
Emory Parnell
饰：Chicago policeman O'Doul (uncredited)
Edward Peil Sr.
饰：Policeman (uncredited)
西里尔·环
Cyril Ring
饰：Photographer (uncredited)
Henry Roquemore
饰：Disappointed fan #2 (uncredited)
Art Rowlands
饰：Telephone man (uncredited)
William Roy
饰：Joe Fabrini (uncredited)
Rip Russell
Rip Russell
饰：Laddie (uncredited)
Francis Sayles
饰：Cab driver (uncredited)
安妮塔·夏浦-博尔斯特
Anita Sharp-Bolster
饰：Sasha's mother (uncredited)
C. Montague Shaw
饰：Mr. Worthington (uncredited)
Jack Shea
饰：Hammond (uncredited)
John Sheehan
饰：First paper hanger (uncredited)
杰克·斯图尔特
Jack Stewart
饰：Ed Barrow (uncredited)
Ben Taggart
饰：Conductor (uncredited)
Walter Tetley
饰：Cake delivery boy (uncredited)
Fay Thomas
Fay Thomas
饰：Christy Mathewson (uncredited)
Jimmy Valentine
Jimmy Valentine
饰：Sasha, boy playing baseball (uncredited)
Gohr Van Vleck
饰：Furniture mover (uncredited)
Dorothy Vaughan
饰：Eleanor's landlady (uncredited)
Malcolm Waite
饰：Big strength machine contestant (uncredited)
詹姆斯·韦斯特菲尔德
James Westerfield
饰：Spectator (uncredited)
Guy Wilkerson
Guy Wilkerson
饰：Sportsman at ballgame (uncredited)
Max Willenz
饰：Mr. Colletti (uncredited)
Buddy Williams
饰：Bootblack (uncredited)
查尔斯·威廉姆斯
Charles Williams
饰：Little strength machine contestant (uncredited)
罗伯特·温克勒
Robert Winkler
饰：Murphy (uncredited)
Allen Wood
饰：Freshman telling Lou that Sam wants him (uncredited)
哈利·哈维
Harry Harvey
饰：Joe McCarthy
Ray Noble and His Orchestra
饰：Orchestra,(as Ray Noble and his Orchestra)